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    Y17G9B.4 Peptidyl-prolyl cis-trans isomerase [ Caenorhabditis elegans ]

    Gene ID: 177245, updated on 27-Dec-2024

    Summary

    Official Symbol
    Y17G9B.4
    Official Full Name
    Peptidyl-prolyl cis-trans isomerase
    Primary source
    WormBase:WBGene00021201
    Locus tag
    CELE_Y17G9B.4
    See related
    AllianceGenome:WB:WBGene00021201
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Orthologous to human PPID (peptidylprolyl isomerase D). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y17G9B.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (4752119..4753227)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Large ribosomal subunit protein eL20 Neighboring gene Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Neighboring gene F-box associated domain-containing protein Neighboring gene PID domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Peptidyl-prolyl cis-trans isomerase
    NP_500632.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4752119..4753227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068231.7NP_500632.3  Peptidyl-prolyl cis-trans isomerase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500632.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N579
      Conserved Domains (1) summary
      cl00197
      Location:99252
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    RNA

    1. NR_131472.1 RNA Sequence

      Status: REVIEWED