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    fimC type 1 fimbriae periplasmic chaperone [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948843, updated on 3-Dec-2024

    Summary

    Official Symbol
    fimC
    Official Full Name
    type 1 fimbriae periplasmic chaperone
    Primary source
    ECOCYC:EG10310
    Locus tag
    b4316
    See related
    ASAP:ABE-0014149
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4307; pilB
    Summary
    FimC has Ig-like domains: pfam PF00345 aligns to N-terminal residues 37-157, and pfam PF02753 aligns to C-terminal residues 161-237. [More information is available at EcoGene: EG10310]. FimC is a member of the periplasmic chaperone family which functions in the chaperone-usher pathway and is indispensable in the biogenesis of the type 1 pilus fiber of Escherichia coli . [More information is available at EcoCyc: EG10310].
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    Genomic context

    Sequence:
    NC_000913.3 (4544304..4545029)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene type 1 fimbriae major subunit Neighboring gene putative fimbrial protein FimI Neighboring gene type I fimbriae usher protein Neighboring gene type 1 fimbriae minor subunit FimF

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein folding chaperone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein folding chaperone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chaperone-mediated protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within chaperone-mediated protein folding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in chaperone-mediated protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in outer membrane-bounded periplasmic space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    type 1 fimbriae periplasmic chaperone

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4544304..4545029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418736.3 type 1 fimbriae periplasmic chaperone [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418736.3

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      D2SX14
      Conserved Domains (1) summary
      PRK15195
      Location:21237
      PRK15195; molecular chaperone FimC