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    srlA sorbitol-specific PTS enzyme IIC2 component [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947575, updated on 17-Dec-2024

    Summary

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    Official Symbol
    srlA
    Official Full Name
    sorbitol-specific PTS enzyme IIC2 component
    Primary source
    ECOCYC:G8210
    Locus tag
    b2702
    See related
    ASAP:ABE-0008890
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2697; gutA; sbl; srlA-1
    Summary
    Membrane topology predictions using experimentally determined C terminus locations indicate that SrlA has 3 transmembrane helices and the C-terminus is located in the cytoplasm . [More information is available at EcoCyc: G8210].
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    Genomic context

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    Sequence:
    NC_000913.3 (2825832..2826395)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene NMN aminohydrolase Neighboring gene membrane-bound lytic murein transglycosylase B Neighboring gene sorbitol-specific PTS enzyme IIBC1 component Neighboring gene sorbitol-specific PTS enzyme IIA component Neighboring gene sorbitol-6-phosphate 2-dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A specialized transducing phage, lambda psrlA, for the sorbitol phosphotransferase of Escherichia coli K12. Boronat A, et al. J Gen Microbiol, 1982 Mar. PMID 6281366
    2. Xylitol and D-arabitol toxicities due to derepressed fructose, galactitol, and sorbitol phosphotransferases of Escherichia coli. Reiner AM. J Bacteriol, 1977 Oct. PMID 334721, Free PMC Article
    3. Physical mapping of the srl recA region of Escherichia coli: analysis of Tn10 generated insertions and deletions. Willis DK, et al. Mol Gen Genet, 1981. PMID 6278241
    4. Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum. Reizer J, et al. Curr Microbiol, 1996 Nov. PMID 8875915
    5. Genetic analysis of the Escherichia coli K-12 srl region. McEntee K. J Bacteriol, 1977 Dec. PMID 336611, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in sorbitol transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sorbitol-specific PTS enzyme IIC2 component
    YP_026180.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2825832..2826395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026180.1 sorbitol-specific PTS enzyme IIC2 component [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026180.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A447X2C8
      Conserved Domains (1) summary
      TIGR00821
      Location:1 → 181
      EII-GUT; PTS system, glucitol/sorbitol-specific, IIC component
    Nucleotide Protein
    Heading Accession and Version

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