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    mtr tryptophan:H(+) symporter Mtr [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947675, updated on 3-Dec-2024

    Summary

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    Official Symbol
    mtr
    Official Full Name
    tryptophan:H(+) symporter Mtr
    Primary source
    ECOCYC:EG10617
    Locus tag
    b3161
    See related
    ASAP:ABE-0010387
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3149
    Summary
    TyrR regulon. [More information is available at EcoGene: EG10617]. Mtr is one of three known transporters for tryptophan in Escherichia coli, the others being TnaB and AroP. [More information is available at EcoCyc: EG10617].
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    Genomic context

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    Sequence:
    NC_000913.3 (3304573..3305817, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ubiquinone biosynthesis protein UbiV Neighboring gene putative luciferase-like monooxygenase YhbW Neighboring gene ATP-dependent RNA helicase DeaD Neighboring gene uncharacterized protein YrbN Neighboring gene lipoprotein NlpI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Membrane topology analysis of Escherichia coli K-12 Mtr permease by alkaline phosphatase and beta-galactosidase fusions. Sarsero JP, et al. J Bacteriol, 1995 Jan. PMID 7814318, Free PMC Article
    2. 5-methyltryptophan-resistant mutations lniked with the arginine G marker in Escherichia coli. Hiraga S, et al. J Bacteriol, 1968 Nov. PMID 4882032, Free PMC Article
    3. The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12. Heatwole VM, et al. J Bacteriol, 1991 Jun. PMID 1904443, Free PMC Article
    4. Formation of aromatic amino acid pools in Escherichia coli K-12. Brown KD. J Bacteriol, 1970 Oct. PMID 4919744, Free PMC Article
    5. Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12. Heatwole VM, et al. J Bacteriol, 1991 Jan. PMID 1987112, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-tryptophan transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aromatic amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aromatic amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tryptophan transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tryptophan:H(+) symporter Mtr

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3304573..3305817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417630.1 tryptophan:H(+) symporter Mtr [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417630.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377DAG2
      Conserved Domains (1) summary
      PRK10483
      Location:1 → 414
      PRK10483; tryptophan permease; Provisional
    Nucleotide Protein
    Heading Accession and Version

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