U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nrfC putative menaquinol-cytochrome c reductase 4Fe-4S subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948581, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nrfC
    Official Full Name
    putative menaquinol-cytochrome c reductase 4Fe-4S subunit
    Primary source
    ECOCYC:EG11946
    Locus tag
    b4072
    See related
    ASAP:ABE-0013346
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4065; yjcJ
    Summary
    Verified Tat substrate: [More information is available at EcoGene: EG11946]. The nrfC gene encodes a transmembrane Fe-S protein, part of a nitrite reductase reaction, which may transfer electrons from the quinone pool to the c-type cytochromes or it may be an adapter that enables formate dehydrogenase H to transfer electrons into an electrogenic electron-transfer chain. [More information is available at EcoCyc: EG11946].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4289808..4290479)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YtcB Neighboring gene cytochrome c552 nitrite reductase Neighboring gene periplasmic nitrite reductase penta-heme c-type cytochrome Neighboring gene putative menaquinol-cytochrome c reductase subunit NrfD Neighboring gene putative cytochrome c-type biogenesis protein NrfE Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Role of a conserved glutamine residue in tuning the catalytic activity of Escherichia coli cytochrome c nitrite reductase. Clarke TA, et al. Biochemistry, 2008 Mar 25. PMID 18311941
    2. The nitric oxide reductase activity of cytochrome c nitrite reductase from Escherichia coli. van Wonderen JH, et al. J Biol Chem, 2008 Apr 11. PMID 18245085
    3. Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli. Bamford VA, et al. Biochemistry, 2002 Mar 5. PMID 11863430
    4. Respiratory detoxification of nitric oxide by the cytochrome c nitrite reductase of Escherichia coli. Poock SR, et al. J Biol Chem, 2002 Jun 28. PMID 11960983
    5. The Tat system proofreads FeS protein substrates and directly initiates the disposal of rejected molecules. Matos CF, et al. EMBO J, 2008 Aug 6. PMID 18615097, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 4 iron, 4 sulfur cluster binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrite reductase (cytochrome, ammonia-forming) activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within anaerobic electron transport chain RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative menaquinol-cytochrome c reductase 4Fe-4S subunit
    NP_418496.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4289808..4290479
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418496.1 putative menaquinol-cytochrome c reductase 4Fe-4S subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418496.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9Q7D7
      Conserved Domains (1) summary
      TIGR03149
      Location:2 → 223
      cyt_nit_nrfC; cytochrome c nitrite reductase, Fe-S protein
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.