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    gntP fructuronate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948848, updated on 17-Dec-2024

    Summary

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    Official Symbol
    gntP
    Official Full Name
    fructuronate transporter
    Primary source
    ECOCYC:EG12563
    Locus tag
    b4321
    See related
    ASAP:ABE-0014161
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4312; yjiB
    Summary
    Induced by fructuronate, but not gluconate; induced by glucuronate via its conversion to fructuronate. [More information is available at EcoGene: EG12563]. GntP is a member of the GntP family transporters and is homologous to the Escherichia coli GntT and GntU gluconate transporters. [More information is available at EcoCyc: EG12563].
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    Genomic context

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    Sequence:
    NC_000913.3 (4549953..4551296, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene type 1 fimbriae minor subunit FimG Neighboring gene type 1 fimbriae D-mannose specific adhesin Neighboring gene D-mannonate dehydratase Neighboring gene D-mannonate oxidoreductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The gntP gene of Escherichia coli involved in gluconate uptake. Klemm P, et al. J Bacteriol, 1996 Jan. PMID 8550444, Free PMC Article
    2. GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon. Bates Utz C, et al. J Bacteriol, 2004 Nov. PMID 15516583, Free PMC Article
    3. Regulation of hexuronate system genes in Escherichia coli K-12: multiple regulation of the uxu operon by exuR and uxuR gene products. Robert-Baudouy J, et al. J Bacteriol, 1981 Jan. PMID 7007313, Free PMC Article
    4. Target prediction for small, noncoding RNAs in bacteria. Tjaden B, et al. Nucleic Acids Res, 2006. PMID 16717284, Free PMC Article
    5. Classification of 29 families of secondary transport proteins into a single structural class using hydropathy profile analysis. Lolkema JS, et al. J Mol Biol, 2003 Apr 11. PMID 12662917

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. induced by fructuronate and is a new member of the UxuR regulon, and required for growth on fructuronate
      Title: GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables gluconate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables gluconate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gluconate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within gluconate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gluconate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fructuronate transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4549953..4551296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418741.1 fructuronate transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418741.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3L5GYQ5
      Conserved Domains (1) summary
      PRK10034
      Location:1 → 447
      PRK10034; gluconate transporter GntP
    Nucleotide Protein
    Heading Accession and Version

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