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    arpA regulator of acetyl CoA synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944933, updated on 3-Dec-2024

    Summary

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    Official Symbol
    arpA
    Official Full Name
    regulator of acetyl CoA synthetase
    Primary source
    ECOCYC:EG11208
    Locus tag
    b4017
    See related
    ASAP:ABE-0013133
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    arp; ECK4009; yjaC
    Summary
    ArpA was previosly reported to be a regulator of acetyl CoA synthase synthesis based on a personal communication from A. [More information is available at EcoGene: EG11208]. Lack of arpA is strongly linked to neonatal meningitis caused by some pathogenic Escherichia coli strains . [More information is available at EcoCyc: EG11208].
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    Genomic context

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    Sequence:
    NC_000913.3 (4220301..4222487, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene isocitrate lyase Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase kinase/phosphatase Neighboring gene DNA-binding transcriptional repressor IclR Neighboring gene cobalamin-dependent methionine synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of an anonymous molecular marker strongly linked to Escherichia coli strains causing neonatal meningitis. Clermont O, et al. J Clin Microbiol, 2004 Apr. PMID 15071045, Free PMC Article
    2. Growth of Escherichia coli in acetate as a sole carbon source is inhibited by ankyrin-like repeats present in the 2',5'-linked oligoadenylate-dependent human RNase L enzyme. Díaz-Guerra M, et al. FEMS Microbiol Lett, 1997 Apr 1. PMID 9103982
    3. Detecting patterns in protein sequences. Neuwald AF, et al. J Mol Biol, 1994 Jun 24. PMID 8014990
    4. The acetate switch. Wolfe AJ. Microbiol Mol Biol Rev, 2005 Mar. PMID 15755952, Free PMC Article
    5. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    regulator of acetyl CoA synthetase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4220301..4222487 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418441.1 regulator of acetyl CoA synthetase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418441.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P23325
      Conserved Domains (1) summary
      pfam07906
      Location:117 → 379
      Toxin_15; ShET2 enterotoxin, N-terminal region
    Nucleotide Protein
    Heading Accession and Version

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