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    iclR DNA-binding transcriptional repressor IclR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948524, updated on 17-Dec-2024

    Summary

    Official Symbol
    iclR
    Official Full Name
    DNA-binding transcriptional repressor IclR
    Primary source
    ECOCYC:EG10491
    Locus tag
    b4018
    See related
    ASAP:ABE-0013136
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4010
    Summary
    Tetrameric IclR binds to the aceBA operator and dimeric IclR is inactive. [More information is available at EcoGene: EG10491]. IclR belongs to the IclR family. [More information is available at EcoCyc: EG10491].
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    Genomic context

    Sequence:
    NC_000913.3 (4222804..4223628, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase kinase/phosphatase Neighboring gene regulator of acetyl CoA synthetase Neighboring gene cobalamin-dependent methionine synthase Neighboring gene putative inorganic phosphate export protein YjbB

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in glyoxylate cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    DNA-binding transcriptional repressor IclR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4222804..4223628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418442.2 DNA-binding transcriptional repressor IclR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418442.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2GKW9, A0A5B9AQU0
      Conserved Domains (1) summary
      PRK11569
      Location:1274
      PRK11569; glyoxylate bypass operon transcriptional repressor IclR