U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Dock9 dedicator of cytokinesis 9 [ Mus musculus (house mouse) ]

    Gene ID: 105445, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Dock9provided by MGI
    Official Full Name
    dedicator of cytokinesis 9provided by MGI
    Primary source
    MGI:MGI:106321
    See related
    Ensembl:ENSMUSG00000025558 AllianceGenome:MGI:106321
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zizimin1; D14Wsu89e; mKIAA1058; B230309H04Rik
    Summary
    Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in positive regulation of GTPase activity. Predicted to be located in endomembrane system and membrane. Is expressed in extraembryonic component; forelimb bud; forelimb bud mesenchyme; and neocortex. Orthologous to human DOCK9 (dedicator of cytokinesis 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 15.8), lung adult (RPKM 13.0) and 24 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Dock9 in Genome Data Viewer
    Location:
    14 E5; 14 65.28 cM
    Exon count:
    63
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (121772026..122038465, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (121538365..121797900, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 15 (oligopeptide transporter), member 1 Neighboring gene STARR-seq mESC enhancer starr_37731 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7355 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122197085-122197385 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122197667-122197968 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122223986-122224286 Neighboring gene STARR-seq mESC enhancer starr_37739 Neighboring gene RIKEN cDNA 1810041H14 gene Neighboring gene STARR-positive B cell enhancer ABC_E10843 Neighboring gene predicted gene 9395 Neighboring gene STARR-positive B cell enhancer ABC_E9906 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122277628-122277929 Neighboring gene ubiquitin associated domain containing 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma. Dai W, et al. Cell Death Dis, 2020 Sep 11. PMID 32917852, Free PMC Article
    2. Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons. Kuramoto K, et al. J Neurosci Res, 2009 Jun. PMID 19156867
    3. Roles of the DOCK-D family proteins in a mouse model of neuroinflammation. Namekata K, et al. J Biol Chem, 2020 May 8. PMID 32241915, Free PMC Article
    4. Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. Nishikimi A, et al. FEBS Lett, 2005 Feb 14. PMID 15710388
    5. The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Jaudon F, et al. Mol Biol Cell, 2015 Jun 1. PMID 25851601, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/beta-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma.
      Title: Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma.
    2. Thus, these results suggest that Zizimin1 plays an important role in dendrite growth in hippocampal neurons through activation of Cdc42.
      Title: Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons.
    Submit: New GeneRIF Correction

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    dedicator of cytokinesis protein 9
    Names
    cdc42 guanine nucleotide exchange factor zizimin-1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081039.1 → NP_001074508.1  dedicator of cytokinesis protein 9 isoform 1

      See identical proteins and their annotated locations for NP_001074508.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC126253, AC165272
      Consensus CDS
      CCDS37018.1
      UniProtKB/TrEMBL
      B2RXS7, F8VPN7
      Related
      ENSMUSP00000047881.8, ENSMUST00000040700.9
      Conserved Domains (5) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1629 → 2069
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:172 → 277
      PH; PH domain
      pfam11878
      Location:60 → 151
      DUF3398; Domain of unknown function (DUF3398)

    2. NM_001128307.1 → NP_001121779.1  dedicator of cytokinesis protein 9 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 3 which is shorter and has distinct N- and C-termini, compared to isoform 1.
      Source sequence(s)
      AC126253, AC165272
      Consensus CDS
      CCDS88728.1
      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      UniProtKB/TrEMBL
      A0A5F8MPL9
      Related
      ENSMUSP00000159030.2, ENSMUST00000239077.2
      Conserved Domains (5) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1621 → 2049
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:186 → 291
      PH; PH domain
      pfam11878
      Location:74 → 165
      DUF3398; Domain of unknown function (DUF3398)

    3. NM_001128308.1 → NP_001121780.1  dedicator of cytokinesis protein 9 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 4 which is shorter and has distinct N- and C-termini, compared to isoform 1.
      Source sequence(s)
      AC126253, AC165272
      Consensus CDS
      CCDS84162.1
      UniProtKB/TrEMBL
      A0A1D5RLE0, B2RY08
      Related
      ENSMUSP00000148328.2, ENSMUST00000212376.3
      Conserved Domains (5) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1620 → 2036
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:186 → 291
      PH; PH domain
      pfam11878
      Location:74 → 165
      DUF3398; Domain of unknown function (DUF3398)

    4. NM_001347596.1 → NP_001334525.1  dedicator of cytokinesis protein 9 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC126253, AC165272, BG076874, BI134428, BM949694, BQ179803, CA557924, CB722727, CF173273, CF532607, CF533751, CF537691, CF539660, CF723234, CK625091, CK637241, CN706706
      Consensus CDS
      CCDS84161.1
      UniProtKB/TrEMBL
      A0A1D5RMM1, B2RXS7
      Related
      ENSMUSP00000148834.2, ENSMUST00000212181.2

    5. NM_134074.2 → NP_598835.2  dedicator of cytokinesis protein 9 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC126253, AC165155, AC165272
      Consensus CDS
      CCDS49569.1
      UniProtKB/TrEMBL
      B2RY79, E9QMR2
      Related
      ENSMUSP00000097872.4, ENSMUST00000100299.11
      Conserved Domains (5) summary
      cd08697
      Location:636 → 825
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1600 → 2014
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:169 → 292
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:174 → 279
      PH; PH domain
      pfam11878
      Location:62 → 153
      DUF3398; Domain of unknown function (DUF3398)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      121772026..122038465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158355.1 → XP_036014248.1  dedicator of cytokinesis protein 9 isoform X8

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2098
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    2. XM_011244881.4 → XP_011243183.1  dedicator of cytokinesis protein 9 isoform X4

      UniProtKB/TrEMBL
      B2RY79
      Conserved Domains (4) summary
      cd08697
      Location:636 → 825
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1632 → 2086
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:169 → 292
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:45 → 155
      DUF3398; Domain of unknown function (DUF3398)

    3. XM_017315759.3 → XP_017171248.1  dedicator of cytokinesis protein 9 isoform X24

      UniProtKB/TrEMBL
      B2RY79
      Conserved Domains (4) summary
      cd08697
      Location:636 → 825
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1609 → 2037
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:169 → 292
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:45 → 155
      DUF3398; Domain of unknown function (DUF3398)

    4. XM_017315757.3 → XP_017171246.1  dedicator of cytokinesis protein 9 isoform X14

      UniProtKB/TrEMBL
      B2RY79
      Conserved Domains (4) summary
      cd08697
      Location:636 → 825
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1609 → 2063
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:169 → 292
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:45 → 155
      DUF3398; Domain of unknown function (DUF3398)

    5. XM_006518358.5 → XP_006518421.1  dedicator of cytokinesis protein 9 isoform X20

      UniProtKB/TrEMBL
      B2RY79
      Conserved Domains (4) summary
      cd08697
      Location:636 → 825
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1632 → 2046
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:169 → 292
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:45 → 155
      DUF3398; Domain of unknown function (DUF3398)

    6. XM_036158360.1 → XP_036014253.1  dedicator of cytokinesis protein 9 isoform X27

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1612 → 2026
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    7. XM_036158357.1 → XP_036014250.1  dedicator of cytokinesis protein 9 isoform X21

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1620 → 2046
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    8. XM_006518357.5 → XP_006518420.1  dedicator of cytokinesis protein 9 isoform X18

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1620 → 2048
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    9. XM_006518350.5 → XP_006518413.1  dedicator of cytokinesis protein 9 isoform X10

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1620 → 2074
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    10. XM_006518348.5 → XP_006518411.1  dedicator of cytokinesis protein 9 isoform X7

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1643 → 2083
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    11. XM_006518345.5 → XP_006518408.1  dedicator of cytokinesis protein 9 isoform X2

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1643 → 2097
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    12. XM_030247579.2 → XP_030103439.1  dedicator of cytokinesis protein 9 isoform X26

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1613 → 2027
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    13. XM_030247578.2 → XP_030103438.1  dedicator of cytokinesis protein 9 isoform X23

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1613 → 2039
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    14. XM_036158358.1 → XP_036014251.1  dedicator of cytokinesis protein 9 isoform X22

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1613 → 2041
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    15. XM_006518352.5 → XP_006518415.1  dedicator of cytokinesis protein 9 isoform X13

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1613 → 2067
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    16. XM_036158359.1 → XP_036014252.1  dedicator of cytokinesis protein 9 isoform X25

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1621 → 2035
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    17. XM_017315758.3 → XP_017171247.1  dedicator of cytokinesis protein 9 isoform X19

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1621 → 2047
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    18. XM_006518356.5 → XP_006518419.1  dedicator of cytokinesis protein 9 isoform X17

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1621 → 2049
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    19. XM_006518349.5 → XP_006518412.1  dedicator of cytokinesis protein 9 isoform X9

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1621 → 2075
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    20. XM_006518355.5 → XP_006518418.1  dedicator of cytokinesis protein 9 isoform X16

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2058
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    21. XM_017315756.3 → XP_017171245.1  dedicator of cytokinesis protein 9 isoform X12

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2070
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    22. XM_006518351.5 → XP_006518414.1  dedicator of cytokinesis protein 9 isoform X11

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2072
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    23. XM_006518347.5 → XP_006518410.1  dedicator of cytokinesis protein 9 isoform X6

      UniProtKB/TrEMBL
      B2RY08
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2084
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    24. XM_006518346.5 → XP_006518409.1  dedicator of cytokinesis protein 9 isoform X3

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2096
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    25. XM_006518344.5 → XP_006518407.1  dedicator of cytokinesis protein 9 isoform X1

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2098
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    26. XM_006518354.5 → XP_006518417.1  dedicator of cytokinesis protein 9 isoform X15

      UniProtKB/Swiss-Prot
      Q8BIK4, Q921Y6
      Conserved Domains (4) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1644 → 2098
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    27. XM_030247584.1 → XP_030103444.1  dedicator of cytokinesis protein 9 isoform X28

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1599 → 2013
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    28. XM_030247583.1 → XP_030103443.1  dedicator of cytokinesis protein 9 isoform X36

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1599 → 2025
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    29. XM_017315765.1 → XP_017171254.1  dedicator of cytokinesis protein 9 isoform X37

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1607 → 2061
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    30. XM_030247582.1 → XP_030103442.1  dedicator of cytokinesis protein 9 isoform X35

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1630 → 2056
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    31. XM_030247581.1 → XP_030103441.1  dedicator of cytokinesis protein 9 isoform X34

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1630 → 2070
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    32. XM_030247580.1 → XP_030103440.1  dedicator of cytokinesis protein 9 isoform X33

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1630 → 2082
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    33. XM_017315755.1 → XP_017171244.1  dedicator of cytokinesis protein 9 isoform X5

      UniProtKB/TrEMBL
      B2RXS7
      Conserved Domains (4) summary
      cd08697
      Location:634 → 823
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11698
      Location:1630 → 2084
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
      cd13267
      Location:167 → 290
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:43 → 153
      DUF3398; Domain of unknown function (DUF3398)

    34. XM_036158362.1 → XP_036014255.1  dedicator of cytokinesis protein 9 isoform X32

      Conserved Domains (1) summary
      cd11698
      Location:672 → 1100
      DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9

    35. XM_006518362.5 → XP_006518425.1  dedicator of cytokinesis protein 9 isoform X30

      Conserved Domains (3) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    36. XM_006518361.5 → XP_006518424.1  dedicator of cytokinesis protein 9 isoform X29

      Conserved Domains (3) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    37. XM_036158361.1 → XP_036014254.1  dedicator of cytokinesis protein 9 isoform X31

      Conserved Domains (3) summary
      cd08697
      Location:648 → 837
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:181 → 304
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:57 → 167
      DUF3398; Domain of unknown function (DUF3398)

    RNA

    1. XR_874271.4 RNA Sequence

    2. XR_383125.5 RNA Sequence

    3. XR_874272.4 RNA Sequence

    4. XR_004938359.1 RNA Sequence

    5. XR_874275.4 RNA Sequence

    6. XR_383126.5 RNA Sequence

    7. XR_383127.5 RNA Sequence

    8. XR_003950813.2 RNA Sequence

    9. XR_003950810.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BIK4.2 GenPept UniProtKB/Swiss-Prot:Q8BIK4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools