U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cynT carbonic anhydrase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946548, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cynT
    Official Full Name
    carbonic anhydrase 1
    Primary source
    ECOCYC:EG10176
    Locus tag
    b0339
    See related
    ASAP:ABE-0001171
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0336
    Summary
    Escherichia coli encodes two carbonic anhydrases, Can and CynT. cynT is encoded in an operon with cynS, the gene encoding cyanase, and its expression is inducible by cyanate . [More information is available at EcoCyc: EG10176].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (358799..359458)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cytosine transporter Neighboring gene cytosine/isoguanine deaminase Neighboring gene DNA-binding transcriptional dual regulator CynR Neighboring gene cyanase Neighboring gene cyanate transporter

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification and characterization of a cyanate permease in Escherichia coli K-12. Sung YC, et al. J Bacteriol, 1989 Sep. PMID 2670891, Free PMC Article
    2. Role of bicarbonate/CO2 in the inhibition of Escherichia coli growth by cyanate. Kozliak EI, et al. J Bacteriol, 1995 Jun. PMID 7768821, Free PMC Article
    3. Why is carbonic anhydrase essential to Escherichia coli? Merlin C, et al. J Bacteriol, 2003 Nov. PMID 14563877, Free PMC Article
    4. Indispensability of the Escherichia coli carbonic anhydrases YadF and CynT in cell proliferation at a low CO2 partial pressure. Hashimoto M, et al. Biosci Biotechnol Biochem, 2003 Apr. PMID 12784642
    5. Bacterial carbonic anhydrases. Kozliak EI, et al. EXS, 2000. PMID 11268536

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Carbonic anhydrase in Escherichia coli. A product of the cyn operon.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbon utilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cyanate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cyanate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    carbonic anhydrase 1
    NP_414873.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      358799..359458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414873.1 carbonic anhydrase 1 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414873.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YF78
      Conserved Domains (1) summary
      cd00884
      Location:7 → 192
      beta_CA_cladeB; Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.