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    agp glucose-1-phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945773, updated on 3-Dec-2024

    Summary

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    Official Symbol
    agp
    Official Full Name
    glucose-1-phosphatase
    Primary source
    ECOCYC:EG10033
    Locus tag
    b1002
    See related
    ASAP:ABE-0003388
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0993
    Summary
    Requires DsbA for activity. [More information is available at EcoGene: EG10033]. Glucose-1-phosphatase, encoded by the agp gene, is a dimeric periplasmic enzyme that shows optimum glucose-1-phosphate hydrolysis activity at pH 4 . [More information is available at EcoCyc: EG10033].
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    Genomic context

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    Sequence:
    NC_000913.3 (1065585..1066826)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene chaperone modulator CbpM Neighboring gene curved DNA-binding protein Neighboring gene uncharacterized protein YccE Neighboring gene PF13993 family protein YccJ Neighboring gene NAD(P)H:quinone oxidoreductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mapping of the Escherichia coli acid glucose-1-phosphatase gene agp and analysis of its expression in vivo by use of an agp-phoA protein fusion. Pradel E, et al. J Bacteriol, 1989 Jun. PMID 2542226, Free PMC Article
    2. Acid phosphatases of Escherichia coli: molecular cloning and analysis of agp, the structural gene for a periplasmic acid glucose phosphatase. Pradel E, et al. J Bacteriol, 1988 Oct. PMID 2844729, Free PMC Article
    3. Purification, crystallization and preliminary X-ray analysis of the Escherichia coli glucose-1-phosphatase. Jia Z, et al. Acta Crystallogr D Biol Crystallogr, 2001 Feb. PMID 11173491
    4. Inositol phosphatase activity of the Escherichia coli agp-encoded acid glucose-1-phosphatase. Cottrill MA, et al. Can J Microbiol, 2002 Sep. PMID 12455612
    5. Functional insights revealed by the crystal structures of Escherichia coli glucose-1-phosphatase. Lee DC, et al. J Biol Chem, 2003 Aug 15. PMID 12782623

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3-phytase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucose-1-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucose-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sugar-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucose-1-phosphatase
    NP_415522.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1065585..1066826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415522.1 glucose-1-phosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415522.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8H9XMP1
      Conserved Domains (1) summary
      PRK10173
      Location:1 → 413
      PRK10173; glucose-1-phosphatase/inositol phosphatase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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