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    Gpr107 G protein-coupled receptor 107 [ Mus musculus (house mouse) ]

    Gene ID: 277463, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gpr107provided by MGI
    Official Full Name
    G protein-coupled receptor 107provided by MGI
    Primary source
    MGI:MGI:2139054
    See related
    Ensembl:ENSMUSG00000000194 AllianceGenome:MGI:2139054
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1624; C530034M11; 9930033D15Rik
    Summary
    Enables clathrin heavy chain binding activity. Acts upstream of or within clathrin-dependent endocytosis. Located in clathrin-coated vesicle and early endosome. Orthologous to human GPR107 (G protein-coupled receptor 107). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 14.2), colon adult (RPKM 13.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gpr107 in Genome Data Viewer
    Location:
    2 B; 2 21.8 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (31042099..31106579)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (31152102..31216567)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39786 Neighboring gene ubiquitin specific peptidase 20 Neighboring gene STARR-positive B cell enhancer ABC_E9195 Neighboring gene STARR-positive B cell enhancer ABC_E4431 Neighboring gene STARR-seq mESC enhancer starr_04135 Neighboring gene formin binding protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E4432 Neighboring gene STARR-positive B cell enhancer ABC_E9196 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:30971715-30971947 Neighboring gene STARR-positive B cell enhancer ABC_E5904 Neighboring gene RIKEN cDNA D330023K18 gene Neighboring gene STARR-seq mESC enhancer starr_04141 Neighboring gene STARR-positive B cell enhancer ABC_E10092 Neighboring gene predicted gene, 22516 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:31112123-31112306 Neighboring gene neuronal calcium sensor 1 Neighboring gene STARR-seq mESC enhancer starr_04149 Neighboring gene hemicentin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables clathrin heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables clathrin heavy chain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in clathrin-dependent endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within clathrin-dependent endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in clathrin-coated vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in clathrin-coated vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178760.4NP_848875.2  protein GPR107 precursor

      See identical proteins and their annotated locations for NP_848875.2

      Status: VALIDATED

      Source sequence(s)
      AK030433, AK034815, BY286814
      Consensus CDS
      CCDS15895.1
      UniProtKB/Swiss-Prot
      Q6ZPL4, Q8BM58, Q8BMN6, Q8BTW1, Q8BUV8
      UniProtKB/TrEMBL
      Q148Z6, Q3U3Y0
      Related
      ENSMUSP00000056739.6, ENSMUST00000056433.7
      Conserved Domains (1) summary
      pfam06814
      Location:214504
      Lung_7-TM_R; Lung seven transmembrane receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      31042099..31106579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001782976.3 RNA Sequence