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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850627, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003955
    Locus tag
    YLL032C
    See related
    AllianceGenome:SGD:S000003955; FungiDB:YLL032C; VEuPathDB:YLL032C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mRNA binding activity. Located in cytoplasm. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Orthologous to human BICC1 (BicC family RNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (74270..76747, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene putative AAA family ATPase RIX7 Neighboring gene Irc19p Neighboring gene mannose-ethanolamine phosphotransferase GPI13 Neighboring gene Rrt7p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of six novel ORFs on the left arm of chromosome XII reveals one gene essential for vegetative growth of Saccharomyces cerevisiae. Zhang N, et al. Yeast, 1999 Sep 15. PMID 10487931
    2. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article
    3. Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations. Brooks MA, et al. Structure, 2010 Sep 8. PMID 20826334
    4. Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. Hannich JT, et al. J Biol Chem, 2005 Feb 11. PMID 15590687
    5. The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis. Lacoux C, et al. Nucleic Acids Res, 2020 Dec 2. PMID 33166396, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding HDA PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_013068.1
    • hypothetical protein; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      74270..76747 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181852.1 → NP_013068.1  TPA: uncharacterized protein YLL032C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013068.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXX3, Q07834
      UniProtKB/TrEMBL
      C7GQE3, N1P1E3
      Conserved Domains (1) summary
      COG5166
      Location:2 → 704
      COG5166; Uncharacterized conserved protein [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07834.1

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