U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TAX4 Tax4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853362, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TAX4
    Official Full Name
    Tax4p
    Primary source
    SGD:S000003619
    Locus tag
    YJL083W
    See related
    AllianceGenome:SGD:S000003619; FungiDB:YJL083W; VEuPathDB:YJL083W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in autophagy; cellular response to starvation; and fungal-type cell wall organization. Located in phagophore assembly site. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TAX4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (278841..280655)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene GTP-Rho binding exocyst subunit EXO70 Neighboring gene Aly2p Neighboring gene Iml2p Neighboring gene Arp4p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Recognition specificity of individual EH domains of mammals and yeast. Paoluzi S, et al. EMBO J, 1998 Nov 16. PMID 9822599, Free PMC Article
    2. Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Bugnicourt A, et al. Traffic, 2008 May. PMID 18298591
    3. Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. Morales-Johansson H, et al. J Biol Chem, 2004 Sep 17. PMID 15265867
    4. A High Copy Suppressor Screen for Autophagy Defects in Saccharomyces arl1Δ and ypt6Δ Strains. Yang S, et al. G3 (Bethesda), 2017 Feb 9. PMID 27974437, Free PMC Article
    5. High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. Garay E, et al. PLoS Genet, 2014 Feb. PMID 24586198, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cellular response to starvation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in fungal-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in phagophore assembly site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Tax4p
    NP_012452.1
    • EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; TAX4 has a paralog, IRS4, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      278841..280655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181516.1 → NP_012452.1  TPA: Tax4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012452.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWA0, P47030
      UniProtKB/TrEMBL
      B3LQ29, C7GR30, N1NZT8
      Conserved Domains (1) summary
      smart00027
      Location:463 → 557
      EH; Eps15 homology domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47030.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools