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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855829, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000006168
    Locus tag
    YPL247C
    See related
    AllianceGenome:SGD:S000006168; FungiDB:YPL247C; VEuPathDB:YPL247C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasm and nucleus. Orthologous to human DCAF7 (DDB1 and CUL4 associated factor 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (82625..84196, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein GYP5 Neighboring gene ncRNA Neighboring gene galactose-responsive transcription factor GAL4 Neighboring gene putative rhomboid protease RBD2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals. de Vetten N, et al. Genes Dev, 1997 Jun 1. PMID 9192870
    2. Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Wilson WA, et al. Mol Cell Proteomics, 2002 Mar. PMID 12096123
    3. The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Goldman A, et al. Mol Cell, 2014 Aug 7. PMID 24930733, Free PMC Article
    4. Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae. Niu W, et al. PLoS Genet, 2008 Jul 11. PMID 18617996, Free PMC Article
    5. The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae. Josefson R, et al. Sci Rep, 2023 Jun 7. PMID 37286562, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_015077.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      82625..84196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184061.1 → NP_015077.1  TPA: uncharacterized protein YPL247C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015077.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3C4, Q12523
      UniProtKB/TrEMBL
      A6ZW09, B5VST7, C8ZID2, G2WNT9
      Conserved Domains (2) summary
      sd00039
      Location:179 → 217
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:177 → 426
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12523.1

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