U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    ESF2 RNA-binding ATPase activator ESF2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855790, updated on 9-Dec-2024

    Summary

    Official Symbol
    ESF2
    Official Full Name
    RNA-binding ATPase activator ESF2
    Primary source
    SGD:S000005337
    Locus tag
    YNR054C
    See related
    AllianceGenome:SGD:S000005337; FungiDB:YNR054C; VEuPathDB:YNR054C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ABT1
    Summary
    Enables ATPase activator activity and RNA binding activity. Involved in ribosomal small subunit biogenesis. Located in nucleolus. Orthologous to human ABT1 (activator of basal transcription 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ESF2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (723356..724306, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene CCR4-NOT core DEDD family RNase subunit POP2 Neighboring gene putative GTPase NOG2 Neighboring gene ncRNA Neighboring gene tRNA-Leu Neighboring gene Hol1p

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATPase activator activity PubMed 
    enables RNA binding  
    enables RNA binding PubMed 
    enables RNA binding  
    enables nucleic acid binding  
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
    involved_in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) PubMed 
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) PubMed 
    involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
    involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) PubMed 
    involved_in rRNA processing  
    involved_in ribosome biogenesis  
    involved_in small-subunit processome assembly  
    involved_in small-subunit processome assembly PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    located_in nucleolus PubMed 
    is_active_in nucleolus  
    located_in nucleolus PubMed 
    located_in nucleolus  
    located_in nucleus  

    General protein information

    Preferred Names
    RNA-binding ATPase activator ESF2
    NP_014452.1
    • Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      723356..724306 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183231.1 → NP_014452.1  TPA: RNA-binding ATPase activator ESF2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014452.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1M9, P53743
      UniProtKB/TrEMBL
      A6ZSC8, B3LPI9, B5VR79, C7GLK3, C8ZFT3, N1NY94
      Conserved Domains (1) summary
      cd12263
      Location:114 → 211
      RRM_ABT1_like; RNA recognition motif (RRM) found in activator of basal transcription 1 (ABT1) and similar proteins
    External link. Please review our privacy policy.