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    SIP5 Sip5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855171, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SIP5
    Official Full Name
    Sip5p
    Primary source
    SGD:S000004748
    Locus tag
    YMR140W
    See related
    AllianceGenome:SGD:S000004748; FungiDB:YMR140W; VEuPathDB:YMR140W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cellular response to glucose starvation. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SIP5 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (547714..549183)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Arf family GTPase CIN4 Neighboring gene serine/threonine protein kinase RIM11 Neighboring gene uncharacterized protein Neighboring gene ribosomal 60S subunit protein L13B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast model uncovers dual roles of mitochondria in action of artemisinin. Li W, et al. PLoS Genet, 2005 Sep. PMID 16170412, Free PMC Article
    2. Sip5 interacts with both the Reg1/Glc7 protein phosphatase and the Snf1 protein kinase of Saccharomyces cerevisiae. Sanz P, et al. Genetics, 2000 Jan. PMID 10628972, Free PMC Article
    3. The Std1 Activator of the Snf1/AMPK Kinase Controls Glucose Response in Yeast by a Regulated Protein Aggregation. Simpson-Lavy K, et al. Mol Cell, 2017 Dec 21. PMID 29249654
    4. Acetic acid inhibits nutrient uptake in Saccharomyces cerevisiae: auxotrophy confounds the use of yeast deletion libraries for strain improvement. Ding J, et al. Appl Microbiol Biotechnol, 2013 Aug. PMID 23828602
    5. Phosphorylation by casein kinase 2 regulates Nap1 localization and function. Calvert ME, et al. Mol Cell Biol, 2008 Feb. PMID 18086883, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to glucose starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sip5p
    NP_013860.1
    • hypothetical protein; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase; forms cytoplasmic foci upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      547714..549183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182642.1 → NP_013860.1  TPA: Sip5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013860.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZW3, P40210
      UniProtKB/TrEMBL
      B3LM28, C7GU78, C8ZEZ6, G2WKJ2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40210.1

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