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    Vmn2r60 vomeronasal 2, receptor 60 [ Mus musculus (house mouse) ]

    Gene ID: 637898, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vmn2r60provided by MGI
    Official Full Name
    vomeronasal 2, receptor 60provided by MGI
    Primary source
    MGI:MGI:3647050
    See related
    Ensembl:ENSMUSG00000090619 AllianceGenome:MGI:3647050
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Casr-rs3; EG637898; Gprc2a-rs3
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r60 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (41765895..41845200)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (42116471..42195776)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 59 Neighboring gene F-box protein 34 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18736 Neighboring gene cyclin B1, pseudogene Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene vomeronasal 2, receptor 61 Neighboring gene vomeronasal 2, receptor, pseudogene 58

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Ho C, et al. Nat Genet, 1995 Dec. PMID 7493018
    2. Identification of putative transmembrane receptor sequences homologous to the calcium-sensing G-protein-coupled receptor. Hinson TK, et al. Genomics, 1997 Oct 15. PMID 9344650
    3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor 60
    Names
    G protein coupled receptor, family C, group 2, member A, related sequence 3
    calcium sensing receptor, related sequence 3
    vomeronasal receptor Vmn2r60

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105057.1 → NP_001098527.1  vomeronasal 2, receptor 60 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AC102494
      Consensus CDS
      CCDS52215.1
      UniProtKB/TrEMBL
      A0A3B2WBC8, L7N2A1
      Related
      ENSMUSP00000156805.2, ENSMUST00000233771.2
      Conserved Domains (4) summary
      cd06365
      Location:36 → 506
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:601 → 835
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:80 → 470
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:515 → 566
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      41765895..41845200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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