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    rpb-10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 [ Caenorhabditis elegans ]

    Gene ID: 171763, updated on 9-Dec-2024

    Summary

    Official Symbol
    rpb-10
    Official Full Name
    DNA-directed RNA polymerases I, II, and III subunit RPABC5
    Primary source
    WormBase:WBGene00021347
    Locus tag
    CELE_Y37E3.3
    See related
    AllianceGenome:WB:WBGene00021347
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion binding activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2L (RNA polymerase II, I and III subunit L). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rpb-10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (2064293..2064686)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF5641 domain-containing protein Neighboring gene Tetratricopeptide repeat protein 5 OB fold domain-containing protein Neighboring gene Modifier of protein aggregation 4 Neighboring gene ADP-ribosylation factor-like protein 13B Neighboring gene ncRNA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC5
    NP_490923.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2064293..2064686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058522.5NP_490923.1  DNA-directed RNA polymerases I, II, and III subunit RPABC5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490923.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9GR61
      Conserved Domains (1) summary
      PLN00032
      Location:167
      PLN00032; DNA-directed RNA polymerase; Provisional