U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    hpo-9 BTB/POZ domain-containing protein 9 [ Caenorhabditis elegans ]

    Gene ID: 179117, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    hpo-9
    Official Full Name
    BTB/POZ domain-containing protein 9
    Primary source
    WormBase:WBGene00015463
    Locus tag
    CELE_C05C8.6
    See related
    AllianceGenome:WB:WBGene00015463
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in adult locomotory behavior; circadian behavior; and modulation of chemical synaptic transmission. Predicted to be active in cytoplasm. Is expressed in body wall musculature; hypodermis; intestine; nervous system; and pharynx. Orthologous to human BTBD9 (BTB domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See hpo-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (7234922..7237130, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene GEX Interacting protein Neighboring gene KRR1 small subunit processome component Neighboring gene Exonuclease domain-containing protein Neighboring gene Centriolar and ciliogenesis-associated protein hyls-1;Hydrolethalus syndrome protein 1 homolog Neighboring gene ATP synthase subunit s, mitochondrial

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. BTBD9 attenuates manganese-induced oxidative stress and neurotoxicity by regulating insulin growth factor signaling pathway. Chen P, et al. Hum Mol Genet, 2022 Jul 7. PMID 35134179, Free PMC Article
    2. Probe the relationship between BTBD9 and MEIS1 in C. elegans and mouse. Lyu S, et al. Exp Results, 2020. PMID 34268480, Free PMC Article
    3. BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome. Lyu S, et al. Brain Struct Funct, 2020 Jul. PMID 32468214, Free PMC Article
    4. Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Walhout AJ, et al. Curr Biol, 2002 Nov 19. PMID 12445390
    5. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome.
      Title: BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in adult locomotory behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in circadian behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in modulation of chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    BTB/POZ domain-containing protein 9
    NP_504839.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7234922..7237130 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072438.5 → NP_504839.1  BTB/POZ domain-containing protein 9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504839.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16313
      Conserved Domains (3) summary
      cd18287
      Location:42 → 161
      BTB_POZ_BTBD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
      cd14822
      Location:165 → 265
      BACK_BTBD9; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
      pfam00754
      Location:461 → 557
      F5_F8_type_C; F5/8 type C domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools