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    tebp-2 SPK domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177337, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tebp-2
    Official Full Name
    SPK domain-containing protein
    Primary source
    WormBase:WBGene00020464
    Locus tag
    CELE_T12E12.3
    See related
    AllianceGenome:WB:WBGene00020464
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tebp-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (5541627..5544748)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Sex-determining protein fem-1 Neighboring gene Dynamin-1-like protein drp-1 Neighboring gene Chromo domain-containing protein Neighboring gene putative E3 ubiquitin-protein ligase ariadne-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Padmanaban S, et al. Proc Natl Acad Sci U S A, 2024 Apr 16. PMID 38588418, Free PMC Article
    2. POT-3 preferentially binds the terminal DNA-repeat on the telomeric G-overhang. Yu X, et al. Nucleic Acids Res, 2023 Jan 25. PMID 36583365, Free PMC Article
    3. The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1. Dietz S, et al. Nat Commun, 2021 May 11. PMID 33976151, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.
      Title: The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SPK domain-containing protein
    NP_500827.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5541627..5544748
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068426.5 → NP_500827.1  SPK domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500827.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22429
    Nucleotide Protein
    Heading Accession and Version

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