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    sec-24.2 uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 178183, updated on 9-Dec-2024

    Summary

    Official Symbol
    sec-24.2
    Official Full Name
    uncharacterized protein
    Primary source
    WormBase:WBGene00004756
    Locus tag
    CELE_ZC518.2
    See related
    AllianceGenome:WB:WBGene00004756
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to be located in ER to Golgi transport vesicle membrane; Golgi apparatus; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in DA neuron. Orthologous to several human genes including SEC24A (SEC24 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See sec-24.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (12355600..12360792, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Bestrophin homolog;Bestrophin homolog 22 Neighboring gene Glutathione S-transferase Neighboring gene poly(A)-specific ribonuclease Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in COPII-coated vesicle cargo loading IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of COPII vesicle coat IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ER to Golgi transport vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    NP_502354.2
    • Product from WormBase gene class sec;
      Confirmed by transcript evidence; yeast SEC homolog

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12355600..12360792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069953.8NP_502354.2  uncharacterized protein CELE_ZC518.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502354.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23368
      Conserved Domains (5) summary
      cd01479
      Location:403643
      Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
      pfam04810
      Location:330366
      zf-Sec23_Sec24; Sec23/Sec24 zinc finger
      pfam04815
      Location:742836
      Sec23_helical; Sec23/Sec24 helical domain
      pfam08033
      Location:644726
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
      cl15697
      Location:860911
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains