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    cyn-7 Peptidyl-prolyl cis-trans isomerase 7 [ Caenorhabditis elegans ]

    Gene ID: 180027, updated on 27-Dec-2024

    Summary

    Official Symbol
    cyn-7
    Official Full Name
    Peptidyl-prolyl cis-trans isomerase 7
    Primary source
    WormBase:WBGene00000883
    Locus tag
    CELE_Y75B12B.2
    See related
    AllianceGenome:WB:WBGene00000883
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to several human genes including PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyn-7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (15186582..15187378, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Mos1 transposase HTH domain-containing protein Neighboring gene Transposase Neighboring gene ncRNA Neighboring gene BTB and MATH domain-containing protein 36 Neighboring gene Peptidyl-prolyl cis-trans isomerase 3

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Peptidyl-prolyl cis-trans isomerase 7
    NP_506749.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15186582..15187378 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074348.11NP_506749.1  Peptidyl-prolyl cis-trans isomerase 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506749.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P52015
      Conserved Domains (1) summary
      cd01926
      Location:4169
      cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...