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    ehn-3 Zinc finger protein ehn-3 [ Caenorhabditis elegans ]

    Gene ID: 191363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ehn-3
    Official Full Name
    Zinc finger protein ehn-3
    Primary source
    WormBase:WBGene00001223
    Locus tag
    CELE_ZK616.10
    See related
    AllianceGenome:WB:WBGene00001223
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Is expressed in somatic gonad precursor. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ehn-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (5416699..5419222, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Saposin B-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TRA-1/GLI controls development of somatic gonadal precursors in C. elegans. Mathies LD, et al. Development, 2004 Sep. PMID 15294864
    2. The C. elegans Hand gene controls embryogenesis and early gonadogenesis. Mathies LD, et al. Development, 2003 Jul. PMID 12756172
    3. hunchback and Ikaros-like zinc finger genes control reproductive system development in Caenorhabditis elegans. Large EE, et al. Dev Biol, 2010 Mar 1. PMID 20026024, Free PMC Article
    4. Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad. Large EE, et al. G3 (Bethesda), 2014 Mar 20. PMID 24402584, Free PMC Article
    5. Somatic sex determination. Zarkower D. WormBook, 2006 Feb 10. PMID 18050479, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in gonad development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in gonad development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Zinc finger protein ehn-3
    NP_001023615.1
    • Confirmed by transcript evidence
    NP_001023616.1
    • Confirmed by transcript evidence
    NP_001023617.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5416699..5419222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028444.3 → NP_001023615.1  Zinc finger protein ehn-3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023615.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2L026, Q65XX7, Q9N4M6
      Conserved Domains (1) summary
      sd00017
      Location:4 → 24
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_001028446.1 → NP_001023617.1  Zinc finger protein ehn-3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023617.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L026

    3. NM_001028445.1 → NP_001023616.1  Zinc finger protein ehn-3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023616.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4M6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q65XX7.1

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