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    lin-24 CABIT domain-containing protein;Immunoglobulin E-set;Iron-sulfur cluster assembly accessory protein [ Caenorhabditis elegans ]

    Gene ID: 178159, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lin-24
    Official Full Name
    CABIT domain-containing protein;Immunoglobulin E-set;Iron-sulfur cluster assembly accessory protein
    Primary source
    WormBase:WBGene00003010
    Locus tag
    CELE_B0001.1
    See related
    AllianceGenome:WB:WBGene00003010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in intestine; nervous system; pharynx; and rectal gland cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lin-24 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (12129504..12135096)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Chromatin target of PRMT1 protein C-terminal domain-containing protein Neighboring gene Palmitoyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative uridine-cytidine kinase;uridine/cytidine kinase Neighboring gene GTP pyrophosphokinase;SET domain-containing protein;Tudor domain-containing protein Neighboring gene MABP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans LIN-24, a homolog of bacterial pore-forming toxin, protects the host from microbial infection. Zhang H, et al. FASEB J, 2023 Oct. PMID 37682220
    2. The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. Soto MC, et al. Genes Dev, 2002 Mar 1. PMID 11877381, Free PMC Article
    3. Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. Galvin BD, et al. Genetics, 2008 May. PMID 18458102, Free PMC Article
    4. Developmental and abnormal cell death in C. elegans. Driscoll M, et al. Trends Neurosci, 1992 Jan. PMID 1374952
    5. Mechanisms and functions of cell death. Ellis RE, et al. Annu Rev Cell Biol, 1991. PMID 1809356

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Caenorhabditis elegans LIN-24, a homolog of bacterial pore-forming toxin, protects the host from microbial infection.
      Title: Caenorhabditis elegans LIN-24, a homolog of bacterial pore-forming toxin, protects the host from microbial infection.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    CABIT domain-containing protein;Immunoglobulin E-set;Iron-sulfur cluster assembly accessory protein
    NP_001255624.1
    • Confirmed by transcript evidence
    NP_001255625.1
    • Confirmed by transcript evidence
    NP_001255626.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12129504..12135096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268695.2 → NP_001255624.1  CABIT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255624.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17410
      Conserved Domains (1) summary
      cl03107
      Location:68 → 193
      ETX_MTX2; Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2

    2. NM_001268696.3 → NP_001255625.1  Immunoglobulin E-set [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255625.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E5QCG5
      Conserved Domains (1) summary
      cl03107
      Location:1 → 104
      ETX_MTX2; Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2

    3. NM_001268697.3 → NP_001255626.1  Iron-sulfur cluster assembly accessory protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E5QCG6
    Nucleotide Protein
    Heading Accession and Version

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