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    osm-7 Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 176790, updated on 9-Dec-2024

    Summary

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    Official Symbol
    osm-7
    Official Full Name
    Uncharacterized protein
    Primary source
    WormBase:WBGene00003887
    Locus tag
    CELE_T05D4.4
    See related
    AllianceGenome:WB:WBGene00003887
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable Notch binding activity. Involved in regulation of gene expression and response to osmotic stress. Predicted to be active in extracellular space. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See osm-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    12
    Sequence:
    Chromosome: III; NC_003281.10 (13576182..13580662)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein PNS1 Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extracellular proteins OSM-7 and OSM-8 are required for stress response gene regulation at all post-embryonic stages. Rodriguez Mendoza V, et al. MicroPubl Biol, 2022. PMID 36606078, Free PMC Article
    2. Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans. Kim YN, et al. Anim Cells Syst (Seoul), 2022. PMID 36275448, Free PMC Article
    3. An extracellular matrix damage sensor signals through membrane-associated kinase DRL-1 to mediate cytoprotective responses in Caenorhabditis elegans. Wimberly K, et al. Genetics, 2022 Mar 3. PMID 34849856, Free PMC Article
    4. Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans. Rohlfing AK, et al. PLoS One, 2010 Feb 2. PMID 20126308, Free PMC Article
    5. OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. Komatsu H, et al. PLoS Biol, 2008 Aug 12. PMID 18700817, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables Notch binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Uncharacterized protein
    NP_001255209.1
    • Confirmed by transcript evidence
    NP_001255210.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13576182..13580662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268280.3 → NP_001255209.1  Uncharacterized protein CELE_T05D4.4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255209.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45750

    2. NM_001268281.3 → NP_001255210.1  Uncharacterized protein CELE_T05D4.4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255210.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C8JQS1
    Nucleotide Protein
    Heading Accession and Version

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