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    dhhc-11 Palmitoyltransferase [ Caenorhabditis elegans ]

    Gene ID: 188748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dhhc-11
    Official Full Name
    Palmitoyltransferase
    Primary source
    WormBase:WBGene00020694
    Locus tag
    CELE_T22E7.2
    See related
    AllianceGenome:WB:WBGene00020694
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in head neurons and spermathecal-uterine junction. Orthologous to several human genes including ZDHHC11 (zinc finger DHHC-type containing 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dhhc-11 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (5764030..5768450)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Cytosolic carboxypeptidase 1 Neighboring gene Uncharacterized protein Neighboring gene LRRCT domain-containing protein Neighboring gene Histone H1.5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Palmitoyltransferase
    NP_491675.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5764030..5768450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059274.5 → NP_491675.3  Palmitoyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491675.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N5D8
      Conserved Domains (2) summary
      pfam01529
      Location:91 → 231
      zf-DHHC; DHHC palmitoyltransferase
      cl01231
      Location:14 → 75
      DUF485; Protein of unknown function, DUF485
    Nucleotide Protein
    Heading Accession and Version

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