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    kbp-5 KNL (kinetochore null) Binding Protein [ Caenorhabditis elegans ]

    Gene ID: 172970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kbp-5
    Official Full Name
    KNL (kinetochore null) Binding Protein
    Primary source
    WormBase:WBGene00016387
    Locus tag
    CELE_C34B2.2
    See related
    AllianceGenome:WB:WBGene00016387
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in kinetochore. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kbp-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (10687363..10688060)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Neighboring gene AGC-kinase C-terminal domain-containing protein;Structural protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores. Varma D, et al. J Cell Biol, 2013 Sep 2. PMID 23979716, Free PMC Article
    2. Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans. Hajeri VA, et al. Cell Div, 2008 Feb 4. PMID 18248670, Free PMC Article
    3. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. Espeut J, et al. J Cell Biol, 2012 Feb 20. PMID 22331849, Free PMC Article
    4. Kinetochores: if you build it, they will come. DeLuca JG, et al. Curr Biol, 2004 Nov 9. PMID 15530383
    5. Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components. Tarailo M, et al. Genetics, 2007 Dec. PMID 18073444, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KNL (kinetochore null) Binding Protein
    NP_492800.1
    • Product from WormBase gene class kbp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10687363..10688060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060399.6 → NP_492800.1  KNL (kinetochore null) Binding Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44956
    Nucleotide Protein
    Heading Accession and Version

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