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    C06A12.3 GSKIP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178529, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C06A12.3
    Official Full Name
    GSKIP domain-containing protein
    Primary source
    WormBase:WBGene00007357
    Locus tag
    CELE_C06A12.3
    See related
    AllianceGenome:WB:WBGene00007357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasm. Orthologous to human GSKIP (GSK3B interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C06A12.3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (17427723..17429602)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene Receptor-type guanylate cyclase gcy-27

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GSKIP domain-containing protein
    NP_001255953.1
    • Partially confirmed by transcript evidence
    NP_001255954.1
    • Partially confirmed by transcript evidence
    NP_001255955.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17427723..17429602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269024.2 → NP_001255953.1  GSKIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255953.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XU41
      Conserved Domains (1) summary
      pfam05303
      Location:142 → 247
      DUF727; Protein of unknown function (DUF727)

    2. NM_001269025.3 → NP_001255954.1  GSKIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255954.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT87
      Conserved Domains (1) summary
      pfam05303
      Location:42 → 147
      DUF727; Protein of unknown function (DUF727)

    3. NM_001269026.3 → NP_001255955.1  GSKIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255955.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT88
      Conserved Domains (1) summary
      pfam05303
      Location:22 → 127
      DUF727; Protein of unknown function (DUF727)
    Nucleotide Protein
    Heading Accession and Version

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