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    • Showing Current items.

    K10B4.3 Protein melted homolog [ Caenorhabditis elegans ]

    Gene ID: 173397, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K10B4.3
    Official Full Name
    Protein melted homolog
    Primary source
    WormBase:WBGene00019615
    Locus tag
    CELE_K10B4.3
    See related
    AllianceGenome:WB:WBGene00019615
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be active in plasma membrane. Orthologous to human VEPH1 (ventricular zone expressed PH domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K10B4.3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (114428..121221, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene Cationic amino acid transporter C-terminal domain-containing protein Neighboring gene Ntox44 domain-containing protein;Peptidase S1 domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Neuromedin U receptor homolog nmur-2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphatidylinositol-5-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein melted homolog
    NP_493664.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      114428..121221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061263.5 → NP_493664.2  Protein melted homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493664.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O17237
      Conserved Domains (2) summary
      pfam00169
      Location:759 → 864
      PH; PH domain
      cl17171
      Location:757 → 869
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O17237.3

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