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    flp-18 SVPGVLRF-amide 3 [ Caenorhabditis elegans ]

    Gene ID: 180587, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-18
    Official Full Name
    SVPGVLRF-amide 3
    Primary source
    WormBase:WBGene00001461
    Locus tag
    CELE_Y48D7A.2
    See related
    AllianceGenome:WB:WBGene00001461
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable neuropeptide Y receptor binding activity. Involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. Predicted to be located in extracellular space. Is expressed in coelomocyte; head; nervous system; tail; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-18 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (3012190..3014286, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene TransThyretin-Related family domain Neighboring gene ncRNA Neighboring gene Aquaporin-9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Simplified method for cell-specific gene expression analysis in Caenorhabditis elegans. Sugi T, et al. Biochem Biophys Res Commun, 2014 Jul 18. PMID 24942876
    2. Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans. Marks NJ, et al. Biochem Biophys Res Commun, 2001 Sep 7. PMID 11527423
    3. The Brugia malayi neuropeptide receptor-4 is activated by FMRFamide-like peptides and signals via Gαi. Anderson RC, et al. Mol Biochem Parasitol, 2014 Jun. PMID 25038481
    4. Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms. Nagy S, et al. Elife, 2014 Dec 4. PMID 25474127, Free PMC Article
    5. Food for thought: a receptor finds its ligand. Potter CJ, et al. Nat Neurosci, 2003 Nov. PMID 14583748

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables neuropeptide Y receptor binding IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of muscle contraction IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sleep IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SVPGVLRF-amide 3
    NP_508514.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3012190..3014286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076113.9 → NP_508514.2  SVPGVLRF-amide 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508514.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86MI4, Q9N4V0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4V0.2

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