skat-1 putative amino acid transporter skat-1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: skat-1
Official Full Name: putative amino acid transporter skat-1
Primary source: WormBase:WBGene00010307
Locus tag: CELE_F59B2.2
See related: AllianceGenome:WB:WBGene00010307
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Predicted to be active in vacuolar membrane. Is expressed in head neurons; intestine; tail neurons; ventral cord neurons; and vulval muscle. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See skat-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (8994645..8996786, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F59B2.2 (e-PCR)
- UniSTS:307728

F59B2.3 (e-PCR)
- UniSTS:311294

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in L-alpha-amino acid transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in amino acid transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in amino acid transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in vacuolar membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative amino acid transporter skat-1

NP_498989.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8994645..8996786 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066588.7 → NP_498989.1 putative amino acid transporter skat-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498989.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P34479, Q9U3E0

Conserved Domains (2) summary

COG0814
Location:40 → 448

SdaC; Amino acid permease [Amino acid transport and metabolism]

pfam01490
Location:35 → 446

Aa_trans; Transmembrane amino acid transporter protein