U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F26E4.7 FAS1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172829, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    F26E4.7
    Official Full Name
    FAS1 domain-containing protein
    Primary source
    WormBase:WBGene00009162
    Locus tag
    CELE_F26E4.7
    See related
    AllianceGenome:WB:WBGene00009162
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell adhesion and extracellular matrix organization. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in congestive heart failure and corneal dystrophy (multiple). Orthologous to human POSTN (periostin) and TGFBI (transforming growth factor beta induced). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See F26E4.7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    14
    Sequence:
    Chromosome: I; NC_003279.8 (9774165..9779542)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein kinase Neighboring gene DNA-directed RNA polymerase III subunit RPC4 Neighboring gene Cytochrome c oxidase polypeptide VIIc Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Glutathione peroxidase 1 Neighboring gene Ribonuclease 3 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The in-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification. Teuscher AC, et al. Matrix Biol Plus, 2019 Feb. PMID 33543001, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables extracellular matrix structural constituent RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    FAS1 domain-containing protein
    NP_740906.1
    • Confirmed by transcript evidence
    NP_740907.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9774165..9779542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170913.3 → NP_740906.1  FAS1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740906.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90848
      Conserved Domains (2) summary
      smart00554
      Location:530 → 636
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts
      pfam02469
      Location:354 → 484
      Fasciclin; Fasciclin domain

    2. NM_171843.5 → NP_740907.1  FAS1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740907.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3E1
      Conserved Domains (2) summary
      smart00554
      Location:461 → 567
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts
      pfam02469
      Location:298 → 415
      Fasciclin; Fasciclin domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools