U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    sly-1 Sec1 family domain-containing protein 1 [ Caenorhabditis elegans ]

    Gene ID: 185707, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    sly-1
    Official Full Name
    Sec1 family domain-containing protein 1
    Primary source
    WormBase:WBGene00009654
    Locus tag
    CELE_F43D9.3
    See related
    AllianceGenome:WB:WBGene00009654
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable syntaxin binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be active in Golgi membrane. Orthologous to human SCFD1 (sec1 family domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See sly-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    13
    Sequence:
    Chromosome: III; NC_003281.10 (10507058..10518596)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ubiquitin-related modifier 1 homolog Neighboring gene ncRNA Neighboring gene Stress-induced protein 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Gamma-aminobutyric acid receptor subunit beta;Neur_chan_memb domain-containing protein;Neurotransmitter-gated ion-channel ligand-binding domain-containing protein;Neurotransmitter-gated ion-channel transmembrane domain-containing protein;Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges. Rehain-Bell K, et al. Curr Biol, 2017 Mar 20. PMID 28285996, Free PMC Article
    2. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Sec1 family domain-containing protein 1
    NP_001122697.2
    • Confirmed by transcript evidence
    NP_499317.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10507058..10518596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129225.4 → NP_001122697.2  Sec1 family domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122697.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A7LPF3
      Conserved Domains (1) summary
      cl15415
      Location:7 → 653
      Sec1; Sec1 family

    2. NM_066916.4 → NP_499317.2  Sec1 family domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499317.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20364
      Conserved Domains (1) summary
      cl15415
      Location:7 → 650
      Sec1; Sec1 family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.