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    C08F8.2 ATP-dependent RNA helicase SUV3 homolog, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 178022, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C08F8.2
    Official Full Name
    ATP-dependent RNA helicase SUV3 homolog, mitochondrial
    Primary source
    WormBase:WBGene00007444
    Locus tag
    CELE_C08F8.2
    See related
    AllianceGenome:WB:WBGene00007444
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity; DNA helicase activity; and RNA helicase activity. Predicted to be involved in DNA duplex unwinding and mitochondrial RNA 3'-end processing. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial degradosome. Orthologous to human SUPV3L1 (Suv3 like RNA helicase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C08F8.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    13
    Sequence:
    Chromosome: IV; NC_003282.8 (11150997..11154334)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene putative prefoldin subunit 1 Neighboring gene Uncharacterized protein Neighboring gene Membrane Bound O-Acyl transferase, MBOAT Neighboring gene F-box domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
    2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on acid anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mitochondrial RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial degradosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase SUV3 homolog, mitochondrial
    NP_001040912.1
    • Confirmed by transcript evidence
    NP_001255542.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11150997..11154334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047447.5 → NP_001040912.1  ATP-dependent RNA helicase SUV3 homolog, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040912.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      E9P872, Q17828, Q2XN00
      Conserved Domains (5) summary
      cd18805
      Location:336 → 465
      SF2_C_suv3; C-terminal helicase domain of ATP-dependent RNA helicase
      cd17913
      Location:187 → 332
      DEXQc_Suv3; DEXQ-box helicase domain of Suv3
      pfam12513
      Location:606 → 649
      SUV3_C; Mitochondrial degradasome RNA helicase subunit C terminal
      pfam18114
      Location:49 → 166
      Suv3_N; Suv3 helical N-terminal domain
      pfam18147
      Location:536 → 576
      Suv3_C_1; Suv3 C-terminal domain 1

    2. NM_001268613.3 → NP_001255542.1  ATP-dependent RNA helicase SUV3 homolog, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255542.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P872
      Conserved Domains (4) summary
      cd18805
      Location:55 → 184
      SF2_C_suv3; C-terminal helicase domain of ATP-dependent RNA helicase
      pfam18147
      Location:255 → 295
      Suv3_C_1; Suv3 C-terminal domain 1
      pfam12513
      Location:325 → 368
      SUV3_C; Mitochondrial degradasome RNA helicase subunit C terminal
      cl28899
      Location:1 → 51
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q17828.3

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