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    ugt-52 glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 176904, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-52
    Official Full Name
    glucuronosyltransferase
    Primary source
    WormBase:WBGene00018931
    Locus tag
    CELE_F56B3.7
    See related
    AllianceGenome:WB:WBGene00018931
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT8 (UDP glycosyltransferase 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-52 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (778784..784182)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene C2H2-type domain-containing protein Neighboring gene Large ribosomal subunit protein uL2 C-terminal domain-containing protein;Ribosomal_L2_C domain-containing protein Neighboring gene ncRNA Neighboring gene RNA polymerase II-associated protein 1 N-terminal domain-containing protein;RPAP1_N domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronosyltransferase
    NP_499988.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      778784..784182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067587.2 → NP_499988.1  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499988.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45109
      Conserved Domains (2) summary
      pfam00201
      Location:53 → 537
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
      cl10013
      Location:231 → 517
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
    Nucleotide Protein
    Heading Accession and Version

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