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    slc-25A21 Mitochondrial 2-oxodicarboxylate carrier [ Caenorhabditis elegans ]

    Gene ID: 181692, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc-25A21
    Official Full Name
    Mitochondrial 2-oxodicarboxylate carrier
    Primary source
    WormBase:WBGene00011226
    Locus tag
    CELE_R11.1
    See related
    AllianceGenome:WB:WBGene00011226
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. Orthologous to human SLC25A21 (solute carrier family 25 member 21). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slc-25A21 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (16189856..16195007)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene Cilia- and flagella-associated protein 206 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial 2-oxodicarboxylate carrier
    NP_510638.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      16189856..16195007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078237.5 → NP_510638.2  Mitochondrial 2-oxodicarboxylate carrier [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510638.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62347
      Conserved Domains (2) summary
      PTZ00169
      Location:1 → 281
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:8 → 92
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version

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