rsp-6 putative splicing factor, arginine/serine-rich 6 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rsp-6
Official Full Name: putative splicing factor, arginine/serine-rich 6
Primary source: WormBase:WBGene00004703
Locus tag: CELE_C33H5.12
See related: AllianceGenome:WB:WBGene00004703
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable mRNA binding activity. Involved in gonad development and regulation of termination of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including intestine. Orthologous to several human genes including SRSF7 (serine and arginine rich splicing factor 7). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rsp-6 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 6

Sequence:: Chromosome: IV; NC_003282.8 (7789847..7791229, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C33H5.12 (e-PCR)
- UniSTS:315676

C33H5.13 (e-PCR)
- UniSTS:320691

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA binding	NAS Non-traceable Author Statement more info	PubMed
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in RNA splicing	NAS Non-traceable Author Statement more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in gonad development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mRNA cis splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in regulation of termination of DNA-templated transcription	IGI Inferred from Genetic Interaction more info	PubMed
involved_in sex differentiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nuclear speck	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative splicing factor, arginine/serine-rich 6

NP_741446.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

7789847..7791229 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_171383.6 → NP_741446.1 putative splicing factor, arginine/serine-rich 6 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741446.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18409, Q8WSW0, Q8WSW1

Conserved Domains (2) summary

COG0724
Location:2 → 75

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12373
Location:4 → 75

RRM_SRSF3_like; RNA recognition motif in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins