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    rps-23 Small ribosomal subunit protein uS12 [ Caenorhabditis elegans ]

    Gene ID: 178188, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rps-23
    Official Full Name
    Small ribosomal subunit protein uS12
    Primary source
    WormBase:WBGene00004492
    Locus tag
    CELE_F28D1.7
    See related
    AllianceGenome:WB:WBGene00004492
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytosol and rough endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in ribosome. Is expressed in several structures, including anal depressor muscle; excretory cell; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rps-23 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (12390298..12391053, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ig-like domain-containing protein Neighboring gene ncRNA Neighboring gene putative dolichol-phosphate mannosyltransferase subunit 3 Neighboring gene Long-chain-fatty-acid--CoA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased fidelity of protein synthesis extends lifespan. Martinez-Miguel VE, et al. Cell Metab, 2021 Nov 2. PMID 34525330, Free PMC Article
    2. Isolation of eight novel Caenorhabditis elegans small RNAs. Wachi M, et al. Gene, 2004 Jun 23. PMID 15194189
    3. The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans. Davis DE, et al. Genetics, 2009 Aug. PMID 19448268, Free PMC Article
    4. Regulation of the C. elegans molt by pqn-47. Russel S, et al. Dev Biol, 2011 Dec 15. PMID 21989027, Free PMC Article
    5. Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. Fuhrman LE, et al. PLoS Genet, 2009 Sep. PMID 19763173, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in rough endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Small ribosomal subunit protein uS12
    NP_502365.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12390298..12391053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069964.9 → NP_502365.1  Small ribosomal subunit protein uS12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502365.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19877
      Conserved Domains (1) summary
      PTZ00067
      Location:1 → 143
      PTZ00067; 40S ribosomal S23; Provisional

    RNA

    1. NR_131618.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19877.1

    Gene LinkOut

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