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    thn-1 Pathogenesis-related protein 5-like [ Caenorhabditis elegans ]

    Gene ID: 185060, updated on 9-Dec-2024

    Summary

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    Official Symbol
    thn-1
    Official Full Name
    Pathogenesis-related protein 5-like
    Primary source
    WormBase:WBGene00009213
    Locus tag
    CELE_F28D1.3
    See related
    AllianceGenome:WB:WBGene00009213
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See thn-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (12380084..12380900)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein 46 Neighboring gene Protein atz-1 Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Pathogenesis-related protein 5-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. Pukkila-Worley R, et al. PLoS Pathog, 2011 Jun. PMID 21731485, Free PMC Article
    2. Components of the cultivated red seaweed Chondrus crispus enhance the immune response of Caenorhabditis elegans to Pseudomonas aeruginosa through the pmk-1, daf-2/daf-16, and skn-1 pathways. Liu J, et al. Appl Environ Microbiol, 2013 Dec. PMID 24056462, Free PMC Article
    3. Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Cui Y, et al. Genome Biol, 2007. PMID 17592649, Free PMC Article
    4. Transcriptional responses to pathogens in Caenorhabditis elegans. Shivers RP, et al. Curr Opin Microbiol, 2008 Jun. PMID 18567532, Free PMC Article
    5. Genome-wide microarrray analysis reveals roles for the REF-1 family member HLH-29 in ferritin synthesis and peroxide stress response. Quach TK, et al. PLoS One, 2013. PMID 23533643, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Pathogenesis-related protein 5-like
    NP_502360.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12380084..12380900
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069959.3 → NP_502360.1  Pathogenesis-related protein 5-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502360.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19874
      Conserved Domains (1) summary
      cd09218
      Location:21 → 233
      TLP-PA; allergenic/antifungal thaumatin-like proteins: plant and animal homologs
    Nucleotide Protein
    Heading Accession and Version

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