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    nubp-1 Cytosolic Fe-S cluster assembly factor NUBP1 homolog [ Caenorhabditis elegans ]

    Gene ID: 172868, updated on 9-Dec-2024

    Summary

    Official Symbol
    nubp-1
    Official Full Name
    Cytosolic Fe-S cluster assembly factor NUBP1 homolog
    Primary source
    WormBase:WBGene00008664
    Locus tag
    CELE_F10G8.6
    See related
    AllianceGenome:WB:WBGene00008664
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable iron-sulfur cluster binding activity. Involved in regulation of non-motile cilium assembly. Predicted to be located in cilium and cytoplasm. Predicted to be active in cytosol. Is expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Orthologous to human NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nubp-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (10046442..10047977)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ERCC1-like central domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene beta-ketoacyl-[acyl-carrier-protein] synthase I Neighboring gene PH domain-containing protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent FeS chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in iron-sulfur cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of non-motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    Cytosolic Fe-S cluster assembly factor NUBP1 homolog
    NP_492653.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10046442..10047977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060252.8NP_492653.2  Cytosolic Fe-S cluster assembly factor NUBP1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492653.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93459
      Conserved Domains (2) summary
      COG0489
      Location:13282
      Mrp; Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster [Cell cycle control, cell division, chromosome partitioning]
      pfam10609
      Location:56308
      ParA; NUBPL iron-transfer P-loop NTPase