U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gcsh-2 Glycine cleavage system H protein [ Caenorhabditis elegans ]

    Gene ID: 172486, updated on 9-Dec-2024

    Summary

    Official Symbol
    gcsh-2
    Official Full Name
    Glycine cleavage system H protein
    Primary source
    WormBase:WBGene00009918
    Locus tag
    CELE_F52A8.5
    See related
    AllianceGenome:WB:WBGene00009918
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be part of glycine cleavage complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See gcsh-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (7345938..7346723, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene NF-kappa-B inhibitor-interacting Ras-like protein Neighboring gene Innexin-14 Neighboring gene Expressed conserved protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in glycine decarboxylation via glycine cleavage system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycine decarboxylation via glycine cleavage system IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of glycine cleavage complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of glycine cleavage complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Glycine cleavage system H protein
    NP_001369931.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7345938..7346723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383336.2NP_001369931.1  Glycine cleavage system H protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20634
      Conserved Domains (1) summary
      pfam01597
      Location:22142
      GCV_H; Glycine cleavage H-protein