cogc-2 Conserved oligomeric Golgi complex subunit 2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cogc-2
Official Full Name: Conserved oligomeric Golgi complex subunit 2
Primary source: WormBase:WBGene00000585
Locus tag: CELE_C06G3.10
See related: AllianceGenome:WB:WBGene00000585
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIq. Orthologous to human COG2 (component of oligomeric golgi complex 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cogc-2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 9

Sequence:: Chromosome: IV; NC_003282.8 (7036957..7039580, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C06G3.10 (e-PCR)
- UniSTS:308502

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi organization	IEA Inferred from Electronic Annotation more info
involved_in gonad morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of cell migration	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
part_of Golgi transport complex	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Conserved oligomeric Golgi complex subunit 2

NP_501092.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

7036957..7039580 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_068691.8 → NP_501092.1 Conserved oligomeric Golgi complex subunit 2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501092.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q17752, Q21444

Conserved Domains (2) summary

pfam06148
Location:24 → 156

COG2; COG (conserved oligomeric Golgi) complex component, COG2

pfam12022
Location:515 → 633

DUF3510; Domain of unknown function (DUF3510)