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    trpa-2 Ion_trans domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565192, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trpa-2
    Official Full Name
    Ion_trans domain-containing protein
    Primary source
    WormBase:WBGene00010873
    Locus tag
    CELE_M05B5.6
    See related
    AllianceGenome:WB:WBGene00010873
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of transmembrane transporter complex. Is expressed in neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trpa-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (7183053..7185650)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cytoplasmic protein;Flocculation protein FLO11-like;Uncharacterized protein Neighboring gene PhosphoLipase A2 Group

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans TRPA-1 functions in mechanosensation. Kindt KS, et al. Nat Neurosci, 2007 May. PMID 17450139
    2. Studying TRP Channels in Caenorhabditis elegans. Zhu MX, et al. , 2011. PMID 22593955
    3. Evolutionarily conserved, multitasking TRP channels: lessons from worms and flies. Venkatachalam K, et al. Handb Exp Pharmacol, 2014. PMID 24961975, Free PMC Article
    4. Mechanosensation. Goodman MB. WormBook, 2006 Jan 6. PMID 18050466, Free PMC Article
    5. A database of Caenorhabditis elegans behavioral phenotypes. Yemini E, et al. Nat Methods, 2013 Sep. PMID 23852451, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ion_trans domain-containing protein
    NP_492031.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7183053..7185650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059630.7 → NP_492031.1  Ion_trans domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492031.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21517
      Conserved Domains (1) summary
      pfam00520
      Location:119 → 339
      Ion_trans; Ion transport protein
    Nucleotide Protein
    Heading Accession and Version

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