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    mrps-22 Mitochondrial Ribosomal Protein, Small [ Caenorhabditis elegans ]

    Gene ID: 174632, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrps-22
    Official Full Name
    Mitochondrial Ribosomal Protein, Small
    Primary source
    WormBase:WBGene00007564
    Locus tag
    CELE_C14A4.14
    See related
    AllianceGenome:WB:WBGene00007564
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Orthologous to human MRPS22 (mitochondrial ribosomal protein S22). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mrps-22 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (10582618..10584236)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Deoxyhypusine hydroxylase Neighboring gene Small ribosomal subunit protein mS29 Neighboring gene Alpha-1,2-mannosyltransferase algn-9 Neighboring gene Exosome complex component 10 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial Ribosomal Protein, Small
    NP_496281.1
    • Product from WormBase gene class mrps;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10582618..10584236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063880.7 → NP_496281.1  Mitochondrial Ribosomal Protein, Small [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496281.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U3Q0
      Conserved Domains (1) summary
      pfam10245
      Location:40 → 282
      MRP-S22; Mitochondrial 28S ribosomal protein S22
    Nucleotide Protein
    Heading Accession and Version

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