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    nath-10 RNA cytidine acetyltransferase [ Caenorhabditis elegans ]

    Gene ID: 172182, updated on 9-Dec-2024

    Summary

    Official Symbol
    nath-10
    Official Full Name
    RNA cytidine acetyltransferase
    Primary source
    WormBase:WBGene00018866
    Locus tag
    CELE_F55A12.8
    See related
    AllianceGenome:WB:WBGene00018866
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable rRNA cytidine N-acetyltransferase activity and tRNA binding activity. Predicted to be involved in rRNA acetylation involved in maturation of SSU-rRNA. Predicted to be located in nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including excretory cell; germ line; intestine; pharyngeal-intestinal valve; and rectal gland cell. Orthologous to human NAT10 (N-acetyltransferase 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nath-10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    12
    Sequence:
    Chromosome: I; NC_003279.8 (5349646..5353774, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Telomere_reg-2 domain-containing protein Neighboring gene 17-beta-hydroxysteroid dehydrogenase type 6 Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    enables rRNA cytidine N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA acetylation involved in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rRNA modification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in tRNA acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tRNA acetylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA wobble cytosine modification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    RNA cytidine acetyltransferase
    NP_491574.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5349646..5353774 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059173.5NP_491574.1  RNA cytidine acetyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491574.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01757
      Conserved Domains (5) summary
      COG1444
      Location:20914
      TmcA; tRNA(Met) C34 N-acetyltransferase TmcA [Translation, ribosomal structure and biogenesis]
      pfam05127
      Location:279480
      Helicase_RecD; Helicase
      pfam08351
      Location:106200
      DUF1726; Domain of unknown function (DUF1726)
      pfam13718
      Location:521750
      GNAT_acetyltr_2; GNAT acetyltransferase 2
      pfam13725
      Location:780897
      tRNA_bind_2; Possible tRNA binding domain