wdr-83 WD repeat domain-containing protein 83 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: wdr-83
Official Full Name: WD repeat domain-containing protein 83
Primary source: WormBase:WBGene00018014
Locus tag: CELE_F33G12.2
See related: AllianceGenome:WB:WBGene00018014
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human WDR83 (WD repeat domain 83). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See wdr-83 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (5029944..5031712, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F33G12.2 (e-PCR)
- UniSTS:313115

F33G12.3 (e-PCR)
- UniSTS:310097

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WD repeat domain-containing protein 83

NP_494926.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

5029944..5031712 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_062525.6 → NP_494926.1 WD repeat domain-containing protein 83 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_494926.1

Status: REVIEWED

UniProtKB/TrEMBL

Q19986

Conserved Domains (2) summary

cd00200
Location:10 → 294

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:21 → 56

7WD40; WD40 repeat [structural motif]