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    ctr-9 RNA polymerase-associated protein CTR9 [ Caenorhabditis elegans ]

    Gene ID: 176335, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ctr-9
    Official Full Name
    RNA polymerase-associated protein CTR9
    Primary source
    WormBase:WBGene00007184
    Locus tag
    CELE_B0464.2
    See related
    AllianceGenome:WB:WBGene00007184
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. Orthologous to human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ctr-9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (9491640..9497044)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Beta-1,4-mannosyltransferase bre-3 Neighboring gene Neuropeptide-like peptide 36 Neighboring gene Aspartate--tRNA ligase, cytoplasmic Neighboring gene Extracellular superoxide dismutase [Cu-Zn];Superoxide dismutase [Cu-Zn] Neighboring gene pseudo Neighboring gene V-type proton ATPase subunit D

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans. Kubota Y, et al. Dev Biol, 2014 Jul 1. PMID 24721716
    2. The PAF1 complex cell autonomously promotes oogenesis in Caenorhabditis elegans. Kubota Y, et al. Genes Cells, 2022 Jun. PMID 35430776, Free PMC Article
    3. Casein Kinase 1δ Stabilizes Mature Axons by Inhibiting Transcription Termination of Ankyrin. LaBella ML, et al. Dev Cell, 2020 Jan 6. PMID 31910362, Free PMC Article
    4. Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation. Baytek G, et al. Biotechniques, 2022 May. PMID 35297663
    5. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase-associated protein CTR9
    NP_001255000.1
    • Confirmed by transcript evidence
    NP_001255001.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9491640..9497044
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268071.4 → NP_001255000.1  RNA polymerase-associated protein CTR9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255000.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0P268, C0P269, C0P270, Q03560
      Conserved Domains (5) summary
      COG0457
      Location:156 → 442
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:180 → 205
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:357 → 388
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:631 → 706
      TPR_11; TPR repeat
      pfam13424
      Location:473 → 554
      TPR_12; Tetratricopeptide repeat

    2. NM_001268072.4 → NP_001255001.1  RNA polymerase-associated protein CTR9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255001.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03560
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03560.3

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