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    T23G5.2 CRAL-TRIO domain-containing protein T23G5.2 [ Caenorhabditis elegans ]

    Gene ID: 176302, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T23G5.2
    Official Full Name
    CRAL-TRIO domain-containing protein T23G5.2
    Primary source
    WormBase:WBGene00011962
    Locus tag
    CELE_T23G5.2
    See related
    AllianceGenome:WB:WBGene00011962
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in mitochondrial intermembrane space. Predicted to be active in cytoplasm. Is expressed in intestine; nervous system; and reproductive system. Orthologous to several human genes including SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T23G5.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (9231421..9236328, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ribonucleoside-diphosphate reductase large subunit Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Suppressor of activated egl-4 protein 2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CRAL-TRIO domain-containing protein T23G5.2
    NP_001040875.1
    • Confirmed by transcript evidence
    NP_001040876.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9231421..9236328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047410.8 → NP_001040875.1  CRAL-TRIO domain-containing protein T23G5.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040875.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03606, Q03608, Q2EEP6, Q2EEP7
      Conserved Domains (3) summary
      smart00516
      Location:320 → 491
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      smart01100
      Location:256 → 297
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam04707
      Location:17 → 170
      PRELI; PRELI-like family

    2. NM_001047411.5 → NP_001040876.1  CRAL-TRIO domain-containing protein T23G5.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040876.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03606
      Conserved Domains (1) summary
      pfam04707
      Location:17 → 170
      PRELI; PRELI-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03606.3

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