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    F20D6.11 Rieske domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179196, updated on 9-Dec-2024

    Summary

    Official Symbol
    F20D6.11
    Official Full Name
    Rieske domain-containing protein
    Primary source
    WormBase:WBGene00017640
    Locus tag
    CELE_F20D6.11
    See related
    AllianceGenome:WB:WBGene00017640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity, acting on NAD(P)H. Predicted to be involved in execution phase of apoptosis. Predicted to be located in endoplasmic reticulum and mitochondrial inner membrane. Predicted to be active in cytoplasm. Is expressed in anal depressor muscle; body wall musculature; pharynx; reproductive system; and tail. Orthologous to human AIFM3 (apoptosis inducing factor mitochondria associated 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F20D6.11 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (8196774..8199094, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Putative metalloproteinase inhibitor tag-225 Neighboring gene Carboxylic ester hydrolase Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on NAD(P)H IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in execution phase of apoptosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    Rieske domain-containing protein
    NP_505112.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8196774..8199094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072711.5NP_505112.1  Rieske domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19655
      Conserved Domains (2) summary
      cd03478
      Location:29118
      Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
      pfam07992
      Location:147443
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase